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In this study, GLS inhibition reduced glutamine metabolism in prostate cancer cells, significantly decreasing the expression of stem cell markers (such as ALDH, OCT4, and Sox2), with the cells exhibiting reduced stemness characteristics

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Mice were injected intraperitoneally 11 C-labeled 2 beta-carbomethoxy-3 beta-(4-fluorophenyl) tropane ( 11 C-CFT) at a dose of 100 mCi/10 g body weight, dopaminergic transporter (DAT) positron emission tomography (PET) computed tomography (CT) would performed 30 min after injection

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