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In Vitro and Cellular Systems for the Characterization of Bioactivating and Inactivating Drug Metabolizing Enzymes in Adverse Drug Reactions

While other fungal species have multiple gene copies encoding glutathione peroxidase, there is only one glutathione peroxidase homolog in T

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The maximum release at the end of 24 hrs remained in the range of 5 - 35 % when tested using dialysis membrane

Notably, three mutants showed more than a 50% increase in both glutathione parameters compared to the parental strain