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The effect of GLS1 knockdown in GBM cells exometabolome was assessed by 1 H-NMR analysis of the conditioned media (extracellular metabolites)

Instead of a single mold gene, studies point to multiple detoxification and response pathways that each modulate risk for specific mycotoxins, depending on both the exposure level and the genetic variants you carry

A dietary deficit in glycine slows the production of glutathione, hence -glutamyl cysteine is converted into 5-oxoproline

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R.MurchieP.IversenL.et al (2020)