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Low levels of H 2 O 2 can oxidize these residues, leading to their sulfenylation (S-OH), sulfenamidylation (S-N), glutathionylation (S-SG), or disulfide bond formation between protein cysteine residues (S-S)

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Induction of apoptosis was characterized by caspase-3 activation, PARP degradation and the downregulation of Bcl-2

Even though glutathione is one of the best antioxidants (substances that protect cells from damage caused by harmful molecules) of all time, it is still unknown to a large number of people

This process occurs through a post-translational interaction with protease DPP4, which strengthens membrane lipid peroxidation in a protease-independent way via interaction with an ROS-generating NOX (Xie et al., 2017)