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Because the active agent was found circulating in blood, the entire premise from day one was that GHK is a systemic, blood-borne signal rather than a purely local factor

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Wang W, Wu Z, Lin G, Hu S, Wang B, Dai Z, et al

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These results indicated that a GST was required for resistance against O

Nuclear factor erythroid 2-related factor 2 plays a fundamental role in the response to oxidative stress and xenobiotic metabolism and detoxification, and the Nrf2 signaling pathway is intimately associated with development of atherosclerosis