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This cycle helps set the stage for lasting results

These factors limit absorption and systemic action [66]

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No direct causal link has been established by regulatory bodies such as the MHRA or EMA

74, 75, 76, 77, 78 The involvement of DAT expression in cocaines behavioral actions is further supported by the finding that hyperlocomotor responsiveness to cocaine is significantly enhanced in two different mouse models expressing low levels of DAT, 41, 42 likely resulting from reduced basal DAT-mediated DA uptake

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