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doi: 10.1016/j.ctrv.2009.07.002 45 KobayashiH
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183 The TRIM motif (also known as RBCC motif), which identifies this superfamily, consists of a RING domain, one or two B-box domains, N-terminal-associated coiled-coil domain and C-terminal domain
This intermediate is nucleophilically attacked by the active site tyrosine residue (Tyr114) to form a covalent vinylether adduct, leading to inhibition of the enzyme (Figure 6A) (Sun et al., 2009
J Gerontol A Biol Sci Med Sci 50(4):B232B236 Yin YY, Liu H, Cong XB, Liu Z, Wang Q, Wang JZ, Zhu LQ (2010) Acetyl-l-carnitine attenuates okadaic acid induced tau hyperphosphorylation and spatial memory impairment in rats
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