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SAFETY & MONITORING ESSENTIALS: GI effects (nausea, vomiting, diarrhea) typically transient

Constipation, by contrast, tended to persist for longer in some individuals, but it was generally manageable with diet, hydration, or standard remedies

You need 1015% weight loss, which is often sufficient to meaningfully improve metabolic risk, blood pressure, and joint function

Common timeline: First 12 weeks: Side effects may still occur Weeks 35: Side effects typically resolve After 5 weeks: Medication is mostly cleared Side effects usually disappear If side effects persist beyond this period, medical evaluation may be helpful