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When you mobilize stored fat rapidly (which lipotropics do), you generate oxidative byproducts as a natural consequence of beta-oxidation

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Ahmadi S, Bashiri R, Ghadiri-Anari A, Nadjarzadeh A

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The side effects happen about 3 - 4 days a week