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Single tablet preparations may also help overcome poor compliance to prescription NSAID/gastroprotectant regimens (reported at only 68% in one survey) (Goldstein 2006)

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The right dosage, combinations with other therapies, and careful monitoring are critical for success

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doi: 10.1007/s40618-022-01990-5 90 BarreaLMuscogiuriGPuglieseGApranoSde AlteriisGDi SommaCet al

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In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system

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However, these recommendations lack sufficient evaluation of the risk-benefit profile in HS-specific populations, thereby justifying further safety studies

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