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Originally FDA-approved as a Type 2 diabetes treatment, Semaglutide has shown significant promise in recent clinical trials, STEP 1 and STEP 3, for weight loss

A phase 2 RDBPCT in Japan (FLINT-J trial) showed that high doses of OCA (40 mg/day) significantly resolved NASH compared with placebo (38 vs

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While the research remains in early stageswith human trials still aheadit represents a promising direction for addressing both the supply challenges and high costs that have limited access to these increasingly popular medications