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It displaces p53 from the FOXO4 complex, leading to nuclear exclusion of p53 and activation of the intrinsic apoptosis pathway in the senescent cell

When standing up, it can result in insufficient vasoconstriction (e.g., blood vessels are too relaxed)

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Other in vitro studies on human erythrocytes have assessed the induction of eryptosis by OPFRs such as tris(2-chloroethyl) phosphate (TCEP) and tris(1-chloro-2-propyl) phosphate (TCPP)