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Endpoints and assessments The primary endpoint was absolute change from baseline in body weight at week 48
10.1016/j.cmet.2014.05.001 60 WolterJ
Always use a fresh needle for each injection
Cumulative thermal exposure matters more than single-event duration
Furthermore, during the functional neuroimaging phase, it appeared that MC4R agonism possibly amplified activity in the cerebellar and supplementary motor areas while possibly deactivating the secondary somatosensory cortex, specifically when the subjects were exposed to erotic stimuli, in contrast to the placebo
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