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Retatrutide adds glucagon receptor activation on top of that, producing the most significant weight loss of any peptide studied to date

Generally, you start tirzepatide at the lowest dose regardless of your semaglutide dose, then escalate based on response

This is a question strictly for your healthcare provider

Most patients (98.1%) used one or more antihyperglycemic medications at baseline

You may experience some GI upset or other side effects

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