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Bottom line: Zinc supplementation may help improve ADHD symptoms in some children, particularly those who are zinc-deficient

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Proposed Mechanism BPC-157 appears to work through multiple pathways: Maintaining vesicular integrity (affecting VMATs and dopamine transporters) Possibly occupying its own vesicular storage sites Competing for dopamine receptor binding Functionally substituting when dopaminergic neurons are lost This last property, essentially filling in for missing dopamine function, would explain why the peptide counteracts both receptor agonists (apomorphine) and antagonists (haloperidol, fluphenazine, clozapine, sulpiride) with equal effectiveness

doi: 10.3389/fneur.2023.1103416 114 QuY.YanM.ZhangQ

Charles USA Been using this for years with great results, and now use their MANO-B complex which has the same ingredients