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Dosage can increase in 1.5 milligrams increments after 4 weeks on the previous dosage

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Furthermore, mitochondrial GSH depletion seems to be more important that cytosolic depletion, since 3-hydroxyacetanalide (AMAP), an APAP isomer, produces a similar degree of cytosolic GSH depletion to that produced by APAP, but without producing hepatotoxicity (48)

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