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[6] [7] For weight management, NICE technology appraisals (TA875 for Wegovy, TA664 for Saxenda) specify use within specialist weight management services for people with a BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) and following unsuccessful lifestyle interventions

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As a first-in-class triple receptor agonist , it has demonstrated robust metabolic effects in early clinical studies

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Severity often correlates with the speed of dose escalation

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