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An important regulatory note: On December 22, 2025, the FDA approved Novo Nordisk's Wegovy tablet (oral semaglutide 25 mg) as the first oral GLP-1 receptor agonist for chronic weight management, with a national launch in January 2026

WHO's Conditional Recommendation The WHO's conditional recommendation represents the organization's first formal endorsement of GLP-1 therapies for obesity management

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How effective are GLP-1 medications for weight loss

Linagliptin: cough, increased amylase and lipase levels