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For most people the honest answer is: often at first, then much less often once your stores are refilled

Jimnez et al., 2005

Popular alternative delivery methods include: Note, it is highly unlikely that the often prescribed 50mcg tablets will be of any use to patients with Autoimmune Pernicious Anaemia

Patients even concentrate their food in just one meal a day because they know they're going to be very sick

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Then theres the issue of misuse and dependence