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Considering the fact that other tests were done to rule out other infections, such as bacterial and viral infections, that could produce similar biochemical changes, the poor malaria diagnostic potential of these parameters could then be due to the influence of other factors such as diet, absorption, excretion, nutritional status, oxidative effect of artemisinins, individual differences in response to artemisinin treatment, level of parasitaemia and state of host immunity

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ensure adequate iron, folate, vitamin D, zinc, magnesium, and iodine

Zhangs study demonstrated that the synthesis of GSH is intricately linked to serine metabolism, with its metabolic byproducts lactate and 2-hydroxyglutarate (2-HG) suppressing the cytotoxic function of T cells