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10.3389/fmolb.2022.1002710 79 MetereA.GiacomelliL

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Adverse effects: Orlistat-associated to liver failure Orlistat, a drug inhibiting pancreatic lipase and aimed at aiding weight loss, has been linked to severe liver-related side effects, including the formation of gallstones, liver inflammation with bile obstruction, and acute liver failure, as highlighted in various studies [5, 42, 66,67,68,69]

The resulting triple mechanism produces weight loss approximately 8 percentage points higher than tirzepatide and 14 percentage points higher than semaglutide

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