Adverse event reports submitted to the FDA have highlighted severe gastrointestinal issues, such as gastroparesis and bowel obstruction, associated with Ozempic and similar drugs
For example, if a patient develops intractable vomiting at 1.7 mg, the prescriber will typically return them to 1.0 mg for an additional four weeks before re-attempting the increase
So this is an area where there is a need to develop new treatments. Mahavir Agarwal, a psychiatrist who coleads the Mental Health and Metabolism Clinic at the Centre for Addiction and Mental Health, says GLP-1 drugs are worth investigating if only for antipsychotic side effect management in people with psychiatric conditions
Redox Signal 8 , 243270, (2006)
1 The findings fueled even greater excitement over the seemingly limitless therapeutic uses of GLP-1 drugsnot only could they promote weight loss and glycemic control, but they also appeared to have the additional effect of cardiovascular protection
Occasional missed doses have minimal long-term impact if you quickly resume your schedule