glp gip tirzepatide Effects of tirzepatide, a dual and GLP-1 receptor agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats Insights into the Mechanism of

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Thus, these AD-inducing agents are helpful pharmacological tools to study, to some extent, the cellular and molecular changes related to AD pathogenesis

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Furthermore, GLP-1 (43, 44) and liraglutide (45) may suppress oxLDL-induced foam-cell formation from M2-macrophages, retarding atherosclerotic lesion development in experimental models (45)

Future research should focus on unraveling these mechanisms further, providing opportunities for developing novel therapeutic strategies that can mitigate ferroptosis and improve outcomes for individuals affected by COPD