B12 is an important nutrient that is often used as a nutritional supplement, even by those without a B12 deficiency
Mechanism : Improved cavernous blood flow Improved cavernous oxygen concentration Mechanical dilatation of cavernous arteries and/or mechanical stretching of cavernous and tunical tissues
This route fits patients pursuing systemic regenerative protocols, wound healing support, or broader anti-aging programs where systemic distribution is the goal, not routine skin or hair maintenance
That said, peptide bonds and certain side chains can still undergo slow chemical degradation over time, accelerated by light, heat, and oxygen exposure
Some bacteria can quickly cause illness
This metabolic regulatory function may synergize with caloric restriction, which is a strategy proven to impede the development of lupus-like disease in New Zealand Black (NZB) and NZBNew Zealand White (NZW) F1 mice (161, 162)