10.1016/j.pcad.2019.07.005 [DOI] [PubMed] [Google Scholar] Gault, V
Despite a small detectable increase in birth weight of newborns from GLP-1-exposed pregnancies, there was no increased risk of large or small for gestational age birth weight or cesarean delivery associated with pre-pregnancy or early pregnancy GLP-1 use, Maya and colleagues wrote
These precautions are in place to ensure the safe and effective use of the medication, adhering to regulatory guidelines for its approved uses
Glutamine can undergo deamidation, while aspartic acid may isomerize to isoaspartic acid, affecting stability
Visceral fat likely decreases at a slightly faster rate than subcutaneous fat, consistent with the higher beta-3 receptor density in visceral adipose tissue
Like TRIUMPH-1, this is a basket trial with nested OSA/OA substudies but enrolling participants who also have type 2 diabetes