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He walks through the data and compares the effectiveness of the two drugs, the side effects, and perhaps more importantly, his reservations around wide use of these drugs and who he would consider to be a candidate for them

68,69 Therefore, an extra incentive exists for using them in patients suffering from multiple comorbidities

Multi-receptor action changes metabolism in a way that is more powerful than single-pathway activation

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When the skin captures UV radiation, keratinocytes produce -MSH (alpha-melanocyte stimulating hormone), a peptide hormone that binds to melanocytes and stimulates them to produce melanin , a pigment that absorbs UV and protects DNA from damage

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