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J Neuroendocrinol

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3.2 Quality assessment and risk of bias According to the Jadad scale for RCTs (n = 13) (Yazaki et al., 2006

Retrieved from (licensed in all 50 states) Bean, M

No tolerance development to the lipolytic effects was noted in these studies, suggesting that unlike beta-2 agonists (which rapidly desensitize their receptors), beta-3 receptor activation may not produce the same downregulation pattern

It mimics the effects of the human growth hormone to influence fat metabolism without the muscle-building effects typically associated with growth hormone therapies