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In addition, as an endotoxin, LPS can inhibit the activity of hepatic type I iodothyronine deiodinase (D1) and conversely activates type II iodothyronine deiodinase (D2) in the hypothalamus and anterior pituitary, thus promoting the conversion of thyroxine (T4) to triiodothyronine (T3) [192, 193]

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doi: 10.1371/journal.pone.0183541 200 ZhengXXuFLiangHCaoHCaiMXuWet al

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