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In addition, the number of stools per week was increased with acacia gum (10 and 15 g/day) and daily stool weight was higher during acacia gum consumption

Nature 436 , 720724 (2005)

In Vitro: Dihexa binds with high affinity to HGF and both dihexa and its parent compound Norleucine 1-AngIV induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF-dependent cell scattering. Further, dihexa and Nle1-AngIV induce hippocampal spinogenesis and synaptogenesis similar to HGF itself. Dihexa effectively inhibits HGF dimerization at 1 M. While dihexa at 1 nM and 10 pM alone does not activate c-Met, it markedly augments the capacity of HGF at 1.25 and 2.5 ng/mL to activate c-Met

Am J Physiol Cell Physiol (2004) 286:C1195202

Simply inverting the container a couple of times before ingesting is adequate.* Q