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Alternatives to Microdosing Patients concerned about side effects or cost have several safer alternatives to microdosing

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Nutrition 26:112119 Kandil S, Brennan L, McBean GJ (2010) Glutathione depletion causes a JNK and p38 MAPK -mediated increase in expression of cystathionine--lyase and upregulation of the transsulfuration pathway in C6 glioma cells

Pharmacologic blockade of IGF-1R, AKT, or MEK-ERK abrogated this effect, implicating canonical IGF-1 signaling in checkpoint regulation