This is important because GLP-1 drugs were originally designed to have a long half-life in blood to maximise their efficacy in the treatment of diabetes which prevents them from entering the brain (Hlscher)
Understanding New Weight-Loss Drugs. Harvard Health, Harvard Health Publishing, 1 Nov
Tirzepatide dosing follows a similar escalation pattern from 2.5mg through 5mg, 7.5mg, 10mg, 12.5mg, and 15mg
doi: 10.1530/JOE-13-0221 28 PykeCHellerRSKirkRKrskovCReedtz-RungeSKaastrupPet al
Tirzepatide has a shorter half-life of about five days, according to the Zepbound label
Even as MEDVi was generating the kind of revenue that would land it in the New York Times, the relationships powering that growth were already falling apart