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Structurally, MT-II is classed as a cyclic heptapeptide, displaying a lactic ring and truncated form

The liver, thyroid, pancreas and adrenal glands all feed into and respond to this same hormonal network, and the wider effects of peptides on these organs remain largely unknown

The activation of an intracellular cascade of biochemical reactions results in the phosphorylation of zona occludens (ZO) protein and myosin, as well as actin polymerization

Statements Author contributions LL: writing-original draft

doi: 10.1038/s41367-019-0009-1 4 HalesCMCarrollMDFryarCDOgdenCL

10.1097/DBP.0000000000001334 163 YangC.-J.LiuC.-L.SangB.ZhuX.-M.DuY.-J