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12-week protocols exist but may show diminishing returns

-Helical structures endow peptides with the powerful capability of binding to target proteins involved in -helix-mediated PPIs as the modulators of PPI, which is essential to pre-organize into the bound conformations

Koytchev R, Alken RG, Dundarov S

Psychiatry 76 , 917926 (2014)

2018 May 1;9:419.

Previously, these treatments required patients to self-administer injections on a regular basis, which could be a barrier to adherence for many individuals