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Beginning your new medication too early can raise the risk of gastrointestinal discomfort (such as nausea or vomiting) or other compounded side effects

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Am J Physiol Renal Physiol 2008;295:F1648F1657

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While conclusive evidence is pending, the convergence of mechanistic, preclinical, and clinical data makes GLP-1 inhibitors one of the most promising emerging approaches to substance use disorders

Michell et al., 1999