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Thereby, catechin and taxifolin were mainly present in blood cells while 5-(3,4-dihydroxyphenyl)--valerolactone, ferulic acid and caffeic acid preferentially resided in synovial fluid of osteoarthritis patients

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Given that neuronal atrophy is largely driven by cerebral hypoperfusion and hypometabolism, a restoration in CBF via exercise has been shown to reverse or attenuate the rate of white matter damage (Macaulay et al., 2022