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We then discuss in detail the metal nanomedicines that have been extensively applied in synergistic cancer therapy, including chemotherapy, photodynamic therapy (PDT), sonodynamic therapy (SDT), chemodynamic therapy (CDT), ferroptotic therapy, and radiotherapy

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To advance the field, there is an urgent need to establish clearer biomarker reference ranges, implement consistent diagnostic criteria, and develop antioxidant treatment protocols grounded in robust clinical evidence

The success of treatment depends on factors such as age, duration of vitiligo, type of vitiligo, affected body areas, and patient adherence

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