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10.1186/s13195-024-01666-7 30 DaiC.HangY.ShostakA.PoffenbergerG.HartN.PrasadN.et al (2017)

Regardless of the strong evidence in preclinical studies, there are limited trials in human populations, primarily due to the heterogeneity of components and the lack of optimized standardization protocols, which precludes their complete clinical use

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The biopsy procedure itself may lead to spontaneous regression of the lesion

Activation of the p62-keap1-nrf2 pathway protects against ferroptosis in hepatocellular carcinoma cells