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This suggestion was further insisted as a potential mechanism of TB-500 by the authors of the research study, who also commented that "transfection of anti-miR-146a nucleotides reversed the inhibitory effect of T4 on IRAK1 and TRAF6." Thus, TB-500 also appears to potentially work for healing by exerting anti-inflammatory action.(6)

Nonetheless, the inflammatory promoting properties of gliadin can be suppressed through the consumption of other dietary phytonutrients including lycopene and quercetin, with the latter previously reported to improve intestinal integrity by elevating TJ protein expression (Ferretti et al