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Originally approved for diabetes, GLP-1 drugs are positively used in the management of weight loss, cardiovascular risk, fatty liver disease, and neurodegenerative conditions

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After stabilization, islets were exposed to 3 mM glucose (basal) followed by 11 mM glucose supplemented with 100 nM test drugs

Additionally, purines function as metabolic signals and play crucial roles in the central nervous system, particularly in the functioning of neuronal and glial cells (Fumagalli et al., 2017)

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