The rate at which appetite suppression occurs can vary from person to person, depending on factors such as your starting dose, how quickly your dose is adjusted, and your unique response to the medication

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doi: 10.1128/mBio.00886-20 60
Thats in part because it belongs to a batch of hormones called incretins, which prompt insulin production in response to food ingestion
If your digestive system isn't working properly, oral supplements can be ineffective
Indirect effects: Any potential benefits observed with these supplements are typically indirect