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To confirm that ESC ferroptosis induced angiogenic cytokine expression (VEGFA and IL8), the primary ESCs were first treated with erastin at different concentrations (10, 20, 30, 50 and 100 M) and for different time periods (0, 3, 6, 9, and 12 h)

150,151 p53 aggregation not only causes the loss of DNA recognition capacity and loss of the proapoptotic function of p53 but also promotes GOF effects

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The key lies in their distinct yet complementary mechanisms of action

Go to the next grave, and say

However, detailed results from these trials have not been published in peer-reviewed journals, limiting comprehensive assessment of clinical efficacy