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In patients with cirrhosis, the main risk factors for developing overt HE include MHE, sarcopenia, hyponatremia, epilepsy, type 2 diabetes, elevated creatinine, elevated bilirubin, and hypoalbuminemia.1 Because overt HE is a manifestation of decompensated liver failure, it has a negative impact on survival

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Administered as a weekly injection or oral tablet, GLP-1 agonists promote sustainable weight loss by mimicking this important hormone to regulate insulin production and improve glycemic control, decreasing appetite when used regularly