The FDA also requires warnings about potential thyroid tumors based on animal studies
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes (SUSTAIN-6, PubMed)
SHOW NOTESTeam NSN website 15
Unknown Pharmacokinetics We dont fully understand how these medications behave in the body at micro-doses, including their absorption, distribution, and elimination patterns
5,6,7 GLP-1 is a peptide produced by the cleavage of proglucagon, mainly synthesized in the intestinal mucosal L-cells, pancreatic islet -cells, and neurons in the nucleus of the solitary tract
Part D still does not cover GLP-1s when theyre used solely for weight loss, and this new $50 pathway sits outside the normal Part D benefit