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In addition, compound 86 showed antioxidant activities and ferric reducing ability of plasma, with IC 50 values of 3.58 g.mL 1 and 58.66 g.mL 1 , respectively, compared to the positive control, ascorbic acid, with 86 being three times more potent for both activities [89]

Kempe et al

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The clinical caution: rapid weight loss (more than 2 pounds per week sustained) increases the risk of gallstones, lean mass loss, and rebound hunger when one medication is later stopped or reduced