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Curated supporting actives may include (but are not limited to): niacinamide (for barrier function and brightening synergy), alphaarbutin (additional tyrosinase modulation), and stable antioxidants (vitamin E derivatives) to protect both skin and glutathione from oxidative breakdown

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Alpha lipoic acid (ALA) regenerates glutathione back to its active form

were the O-pill (norgestrel) oral contraceptive and Narcan (naloxone) opioid overdose nasal spray, which both were approved for OTC in 2023

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