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We also recognize that the evidence is less conclusive for individuals with normal B12 levels

[DOI] [PubMed] [Google Scholar] 38.Stancic-Rokotov D, Sikiric P, Seiwerth S, Slobodnjak Z, Aralica J, Aralica G, Perovic D, Anic T, Zoricic I, Buljat G, Prkacin I, Gjurasin M, Rucman R, Petek M, Turkovic B, Ivasovic Z, Jagic V, Staresinic M, Boban-Blagaic A

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Its 28-day usability window after opening is specifically designed for this use case, and using sterile water in a multi-dose context introduces a real and unnecessary contamination risk with every additional needle insertion

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