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Unequal access to digital devices and reliable internet connectivity, particularly in low- and middle-income countries (LMICs), impedes participation in digital trials

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It has a docking effect with Src homology 2 signal molecules in cells, transferring the signal through Src homology 3 to Son of Sevenless, phosphorylating downstream Ras molecules, thereby activating the extracellular signal-related kinases (ERK1/2) pathway and regulating the growth, proliferation, and differentiation of osteoblasts [26, 27]

This focus addresses a critical gap in the literature, as previous research has primarily centered on patients with type 2 diabetes

95% CI: 0.440.61

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