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Depending on the specific diagnosis, treatment approaches may include: therapeutic exercise chiropractic care anti-inflammatory strategies spinal decompression therapy targeted rehabilitation These approaches aim to reduce irritation of the affected nerve and improve spinal mechanics

Both MOTS-c and metformin activate AMPK through different upstream mechanisms

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doi: 10.1007/s00406-023-01679-7 168 ZhangJ

The inability of antioxidant systems, such as GPX4-dependent pathways, to counteract ROS amplifies ferroptotic damage (90)