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The scientific case for it: A 2006 study by researchers at Baylor University in Texas found that amino acid supplementation before and after exercise increased muscle gains resulting from a 10-week resistance-training program

That is an inference from the variability recognized in current labeling, not a fixed rule

12 mg per week The maximum dose studied, associated with the most pronounced reductions in body weight, with some participants experiencing losses exceeding 24% over a 48-week period

However, they do require behavioral reinforcement

However, for analytical impurity profiling, this is rarely a detriment