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De novo mutations and segregating missense mutations were also observed in males

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Since circulating IGF- 1 levels naturally decline with age [18], our findings have important implications for age-related sarcopenia and microvascular aging (Fig

13 : 909916 Aureli T, Miccheli A, Ricciolini R, Di Cocco ME, Ramacci MT, Angelucci L et al

PSCI affects a significant proportion of survivors, manifesting as deficits in memory, executive function, and attention that markedly diminish quality of life and functional independence

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